Focused methods review
Independent review of a protocol, search, analysis or manuscript at a difficult decision point.
Research & evidence
Evidence that can withstand scrutiny.
We help clinicians, research groups and health organisations make their methods transparent, their analysis defensible and their final claims proportionate to the evidence.
Discuss this serviceAll servicesThe value
What the work should make possible.
- 01
A decision-ready synthesis of what is known and uncertain
- 02
A reproducible method that another researcher can follow
- 03
A stronger protocol, analysis plan, manuscript or reviewer response
Typical deliverables
Specific outputs. Agreed from the outset.
Scope is selected around the decision and current stage. Not every engagement requires every output.
01
PICO or PEO questions, protocols and registration support
02
Database and grey-literature search strategies
03
Deduplication, screening systems and extraction tools
04
Risk-of-bias assessment and GRADE certainty appraisal
05
Meta-analysis, heterogeneity and sensitivity analyses
06
PRISMA-ready manuscripts, figures and supplementary files
07
Clinical study protocols, data dictionaries and analysis plans
08
Journal submission and reviewer-response support
Engagement formats
Support shaped to the work.
Production sprint
A defined block of work that produces a protocol, search, analysis or publication milestone.
End-to-end collaboration
Structured support across the full evidence-synthesis or clinical-research pathway.
Working sequence
A clear route to the next decision.
- 01
Frame
Clarify the decision, question, population, outcomes and limits.
- 02
Plan
Lock the method, safeguards, roles, timeline and outputs.
- 03
Produce
Search, appraise, analyse and document each decision.
- 04
Communicate
Turn the work into a clear, appropriately qualified output.
Published methods in practice
A complex surgical question taken from protocol to meta-analysis.
A registered review combined multi-database searching, duplicate screening, structured risk-of-bias assessment, quantitative synthesis and certainty appraisal while keeping unstable estimates and very-low-certainty evidence explicit.
Outcomes of combined lung cancer resection and lung volume reduction surgery in adults with severe emphysema; a systematic review and meta-analysis
Frontiers in Oncology · 2026 · DOI: 10.3389/fonc.2026.1916431
Co-authored by the founder of Medaxa and Partners; published with the institutional affiliations shown in the journal record.
Let’s move forward
What should this work make possible?
Share the question, current stage, intended audience, timeline and output you need.